Anti-OTC antibody [SRM14799] (STJ11109529)

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STJ11109529
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Host: Rabbit
Applications: WB/IF-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14799
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:1000-1:5000
IF-P, 1:50-1:200
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: OTC
Gene ID: 5009
Uniprot ID: OTC_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity Mainly expressed in liver and intestinal mucosa.
Post Translational Modifications Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.
Function Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion.
Protein Name Ornithine Transcarbamylase - Mitochondrial
Otcase
Ornithine Carbamoyltransferase - Mitochondrial
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-70635
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Ornithine Transcarbamylase - Mitochondrial antibody
Anti-Otcase antibody
Anti-Ornithine Carbamoyltransferase - Mitochondrial antibody
Anti-OTC antibody

Information sourced from Uniprot.org

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