| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
OSTM1 |
| Gene ID: |
28962 |
| Uniprot ID: |
OSTM1_HUMAN |
| Immunogen Region: |
32-284 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 32-284 of human OSTM1 (NP_054747.2). |
| Immunogen Sequence: |
ALPFGSSPHRVFHDLLSEQQ LLEVEDLSLSLLQGGGLGPL SLPPDLPDLDPECRELLLDF ANSSAELTGCLVRSARPVRL CQTCYPLFQQVVSKMDNISR AAGNTSESQSCARSLLMADR MQIVVILSEFFNTTWQEANC ANCLTNNSEELSNSTVYFLN LFNHTLTCFEHNLQGNAHSL LQTKNYSEVCKNCREAYKTL SSLYSEMQKMNELENKAEPG THLCIDVEDAMNITRKLWS |
| Post Translational Modifications | Undergoes proteolytic cleavage in the luminal domain, the cleaved fragments might be linked by disulfide bonds with the remnant of the protein. Highly N-glycosylated. |
| Function | Required for osteoclast and melanocyte maturation and function. |
| Protein Name | Osteopetrosis-Associated Transmembrane Protein 1Chloride Channel 7 Beta Subunit |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Lysosome MembraneSingle-Pass Type I Membrane ProteinRequires Clcn7 To Travel To Lysosomes |
| Alternative Antibody Names | Anti-Osteopetrosis-Associated Transmembrane Protein 1 antibodyAnti-Chloride Channel 7 Beta Subunit antibodyAnti-OSTM1 antibodyAnti-GL antibodyAnti-HSPC019 antibodyAnti-UNQ6098 antibodyAnti-PRO21201 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
