| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OSTF1 |
| Gene ID: | 26578 |
| Uniprot ID: | OSTF1_HUMAN |
| Immunogen Region: | 15-214 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-214 of human OSTF1 (NP_036515.4). |
| Immunogen Sequence: | KVFRALYTFEPRTPDELYFE EGDIIYITDMSDTNWWKGTS KGRTGLIPSNYVAEQAESID NPLHEAAKRGNLSWLRECLD NRVGVNGLDKAGSTALYWAC HGGHKDIVEMLFTQPNIELN QQNKLGDTALHAAAWKGYAD IVQLLLAKGARTDLRNIEKK LAFDMATNAACASLLKKKQG TDAVRTLSNAEDYLDDEDSD |
| Tissue Specificity | Ubiquitously expressed. Present in osteoclasts (at protein level). |
| Function | Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. |
| Protein Name | Osteoclast-Stimulating Factor 1 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Osteoclast-Stimulating Factor 1 antibodyAnti-OSTF1 antibody |
Information sourced from Uniprot.org