Anti-Ornithine Carbamoyltransferase/OTC antibody (STJA0038020)

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STJA0038020
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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Ornithine Carbamoyltransferase/OTC for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification: Affinity Purified
Dilution Range: IHC 1:100-1:200
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: OTC
Gene ID: 5009
Uniprot ID: OTC_HUMAN
Immunogen: A synthesized peptide derived from human Ornithine Carbamoyltransferase
Tissue Specificity Mainly expressed in liver and intestinal mucosa.
Post Translational Modifications Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.
Function Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion.
Protein Name Ornithine Transcarbamylase - Mitochondrial
Otcase
Ornithine Carbamoyltransferase - Mitochondrial
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-70635
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Ornithine Transcarbamylase - Mitochondrial antibody
Anti-Otcase antibody
Anti-Ornithine Carbamoyltransferase - Mitochondrial antibody
Anti-OTC antibody

Information sourced from Uniprot.org

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