Host: |
Rabbit |
Applications: |
WB/IHC-P/ELISA |
Reactivity: |
Human/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
OPN4 |
Gene ID: |
94233 |
Uniprot ID: |
OPN4_HUMAN |
Immunogen Region: |
365-489 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 365-489 of human OPN4 (NP_001025186.1). |
Immunogen Sequence: |
HPKYRVAIAQHLPCLGVLLG VSRRHSRPYPSYRSTHRSTL TSHTSNLSWISIRRRQESLG SESEVGWTHMEAAAVWGAAQ QANGRSLYGQGLEDLEAKAP PRPQGHEAETPGKTKGLIPS QDPRM |
Tissue Specificity | Expressed in the retina. |
Function | Photoreceptor that binds cis-retinaldehydes. Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light. May be involved in the optokinetic visual tracking response. May be involved in the regulation of retinal hyaloid vessel growth and regression. |
Protein Name | MelanopsinOpsin-4 |
Database Links | Reactome: R-HSA-416476Reactome: R-HSA-419771 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionAxonDendritePerikaryon |
Alternative Antibody Names | Anti-Melanopsin antibodyAnti-Opsin-4 antibodyAnti-OPN4 antibodyAnti-MOP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance