| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OPN4 |
| Gene ID: | 94233 |
| Uniprot ID: | OPN4_HUMAN |
| Immunogen Region: | 365-489 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 365-489 of human OPN4 (NP_001025186.1). |
| Immunogen Sequence: | HPKYRVAIAQHLPCLGVLLG VSRRHSRPYPSYRSTHRSTL TSHTSNLSWISIRRRQESLG SESEVGWTHMEAAAVWGAAQ QANGRSLYGQGLEDLEAKAP PRPQGHEAETPGKTKGLIPS QDPRM |
| Tissue Specificity | Expressed in the retina. |
| Function | Photoreceptor that binds cis-retinaldehydes. Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light. May be involved in the optokinetic visual tracking response. May be involved in the regulation of retinal hyaloid vessel growth and regression. |
| Protein Name | MelanopsinOpsin-4 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-419771 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionAxonDendritePerikaryon |
| Alternative Antibody Names | Anti-Melanopsin antibodyAnti-Opsin-4 antibodyAnti-OPN4 antibodyAnti-MOP antibody |
Information sourced from Uniprot.org