| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-OPN4 (365-489) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
OPN4 |
| Gene ID: |
94233 |
| Uniprot ID: |
OPN4_HUMAN |
| Immunogen Region: |
365-489 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 365-489 of human OPN4 (NP_001025186.1). |
| Immunogen Sequence: |
HPKYRVAIAQHLPCLGVLLG VSRRHSRPYPSYRSTHRSTL TSHTSNLSWISIRRRQESLG SESEVGWTHMEAAAVWGAAQ QANGRSLYGQGLEDLEAKAP PRPQGHEAETPGKTKGLIPS QDPRM |
| Tissue Specificity | Expressed in the retina. |
| Function | Photoreceptor that binds cis-retinaldehydes. Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light. May be involved in the optokinetic visual tracking response. May be involved in the regulation of retinal hyaloid vessel growth and regression. |
| Protein Name | MelanopsinOpsin-4 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-419771 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionAxonDendritePerikaryon |
| Alternative Antibody Names | Anti-Melanopsin antibodyAnti-Opsin-4 antibodyAnti-OPN4 antibodyAnti-MOP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
