• STJ71544 Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml) , showing nuclear staining. Actin filaments were stained with phalloidin (red) and the nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
  • STJ71544 Flow cytometric analysis of paraformaldehyde fixed Kelly cells (blue line) , permeabilized with 0. 5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Anti-OAZ antibody (N-Term) (STJ71544)

SKU:
STJ71544-100

€379.38
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Host: Goat
Applications: Pep-ELISA/IF/FC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-OAZ (N-Term) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IF-Strong expression of the protein seen in the nuclei of A431 cells. 10µg/ml
FC-Flow cytometric analysis of Kelly cells. 10ug/ml
ELISA-antibody detection limit dilution 1:2000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ZNF423
Gene ID: 23090
Uniprot ID: ZN423_HUMAN
Immunogen Region: N-Term
Accession Number: NP_055884.2
Immunogen Sequence: EPECDQKTSRALEDR
Function Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation.this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.
Protein Name Zinc Finger Protein 423
Olf1/Ebf-Associated Zinc Finger Protein
Hoaz
Smad- And Olf-Interacting Zinc Finger Protein
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Zinc Finger Protein 423 antibody
Anti-Olf1/Ebf-Associated Zinc Finger Protein antibody
Anti-Hoaz antibody
Anti-Smad- And Olf-Interacting Zinc Finger Protein antibody
Anti-ZNF423 antibody
Anti-KIAA0760 antibody
Anti-NPHP14 antibody
Anti-OAZ antibody

Information sourced from Uniprot.org

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