Anti-NUTF2 antibody (1-127) (STJ115537)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NUTF2 (1-127) antibody for use in WB, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NUTF2 |
| Gene ID | 10204 |
| Uniprot ID | NTF2_HUMAN |
| Immunogen Region | 1-127 |
| Immunogen Sequence | MGDKPIWEQIGSSFIQHYYQ LFDNDRTQLGAIYIDASCLT WEGQQFQGKAAIVEKLSSLP FQKIQHSITAQDHQPTPDSC IISMVVGQLKADEDPIMGFH QMFLLKNINDAWVCTNDMFR LALHNFG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human NUTF2 (NP_005787.1). |
Additional Info
| Function | Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. |
| Protein Name | Nuclear Transport Factor 2Ntf-2Placental Protein 15Pp15 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolNucleus Outer MembraneNucleusNuclear Pore ComplexNucleus Inner MembraneNucleoplasmAt Steady State It Is Essentially NucleoplasmicEnriched In Nucleoplasmic Foci |
| Alternative Antibody Names | Anti-Nuclear Transport Factor 2 antibodyAnti-Ntf-2 antibodyAnti-Placental Protein 15 antibodyAnti-Pp15 antibodyAnti-NUTF2 antibodyAnti-NTF2 antibody |
Information sourced from Uniprot.org