| Short Description : | Rabbit polyclonal NUTF2 (1-127) antibody for use in WB, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NUTF2 |
| Gene ID: | 10204 |
| Uniprot ID: | NTF2_HUMAN |
| Immunogen Region: | 1-127 |
| Immunogen Sequence: | MGDKPIWEQIGSSFIQHYYQ LFDNDRTQLGAIYIDASCLT WEGQQFQGKAAIVEKLSSLP FQKIQHSITAQDHQPTPDSC IISMVVGQLKADEDPIMGFH QMFLLKNINDAWVCTNDMFR LALHNFG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human NUTF2 (NP_005787.1). |
| Function | Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. |
| Protein Name | Nuclear Transport Factor 2Ntf-2Placental Protein 15Pp15 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolNucleus Outer MembraneNucleusNuclear Pore ComplexNucleus Inner MembraneNucleoplasmAt Steady State It Is Essentially NucleoplasmicEnriched In Nucleoplasmic Foci |
| Alternative Antibody Names | Anti-Nuclear Transport Factor 2 antibodyAnti-Ntf-2 antibodyAnti-Placental Protein 15 antibodyAnti-Pp15 antibodyAnti-NUTF2 antibodyAnti-NTF2 antibody |
Information sourced from Uniprot.org
