| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NUTF2 (1-127) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NUTF2 |
| Gene ID: |
10204 |
| Uniprot ID: |
NTF2_HUMAN |
| Immunogen Region: |
1-127 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human NUTF2 (NP_005787.1). |
| Immunogen Sequence: |
MGDKPIWEQIGSSFIQHYYQ LFDNDRTQLGAIYIDASCLT WEGQQFQGKAAIVEKLSSLP FQKIQHSITAQDHQPTPDSC IISMVVGQLKADEDPIMGFH QMFLLKNINDAWVCTNDMFR LALHNFG |
| Function | Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. |
| Protein Name | Nuclear Transport Factor 2Ntf-2Placental Protein 15Pp15 |
| Cellular Localisation | CytoplasmCytosolNucleus Outer MembraneNucleusNuclear Pore ComplexNucleus Inner MembraneNucleoplasmAt Steady State It Is Essentially NucleoplasmicEnriched In Nucleoplasmic Foci |
| Alternative Antibody Names | Anti-Nuclear Transport Factor 2 antibodyAnti-Ntf-2 antibodyAnti-Placental Protein 15 antibodyAnti-Pp15 antibodyAnti-NUTF2 antibodyAnti-NTF2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
