| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Nuclear Pore Membrane Glycoprotein 210 (680-880) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NUP210 |
| Gene ID: |
23225 |
| Uniprot ID: |
PO210_HUMAN |
| Immunogen Region: |
680-880 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 680-880 of human NUP210 (NP_079199.2). |
| Immunogen Sequence: |
QNVTAEDTDSIGLALFAPHS SRNYQQHWILVTCQALGEQV IALSVGNKPSLTNPFPAVEP AVVKFVCAPPSRLTLAPVYT SPQLDMSCPLLQQNKQVVPV SSHRNPRLDLAAYDQEGRRF DNFSSLSIQWESTRPVLASI EPELPMQLVSQDDESGQKKL HGLQAILVHEASGTTAITAT ATGYQESHLSSARTKQPHDP L |
| Tissue Specificity | Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. |
| Post Translational Modifications | N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides. Phosphorylated at Ser-1881 in mitosis specifically.not phosphorylated in interphase. |
| Function | Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. |
| Protein Name | Nuclear Pore Membrane Glycoprotein 210Nuclear Pore Protein Gp210Nuclear Envelope Pore Membrane Protein Pom 210Pom210Nucleoporin Nup210Pore Membrane Protein Of 210 Kda |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-159227Reactome: R-HSA-159230Reactome: R-HSA-159231Reactome: R-HSA-159236Reactome: R-HSA-165054Reactome: R-HSA-168271Reactome: R-HSA-168276Reactome: R-HSA-168325Reactome: R-HSA-168333Reactome: R-HSA-170822Reactome: R-HSA-180746Reactome: R-HSA-180910Reactome: R-HSA-191859Reactome: R-HSA-3108214Reactome: R-HSA-3232142Reactome: R-HSA-3301854Reactome: R-HSA-3371453Reactome: R-HSA-4085377Reactome: R-HSA-4551638Reactome: R-HSA-4570464Reactome: R-HSA-4615885Reactome: R-HSA-5578749Reactome: R-HSA-5619107Reactome: R-HSA-6784531Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9705671 |
| Cellular Localisation | NucleusNuclear Pore ComplexNucleus MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Nuclear Pore Membrane Glycoprotein 210 antibodyAnti-Nuclear Pore Protein Gp210 antibodyAnti-Nuclear Envelope Pore Membrane Protein Pom 210 antibodyAnti-Pom210 antibodyAnti-Nucleoporin Nup210 antibodyAnti-Pore Membrane Protein Of 210 Kda antibodyAnti-NUP210 antibodyAnti-KIAA0906 antibodyAnti-PSEC0245 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and NUP210 knockout (KO) 293T cells, using [KO Validated] NUP210 Rabbit polyclonal antibody (STJ11100771) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89708/358190/STJ11100771_1__36288.1713122505.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and NUP210 knockout (KO) 293T cells, using [KO Validated] NUP210 Rabbit polyclonal antibody (STJ11100771) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.")
