Anti-NUP210 antibody (680-880) (STJ11104329)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Nuclear Pore Membrane Glycoprotein 210 (680-880) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NUP210 |
| Gene ID | 23225 |
| Uniprot ID | PO210_HUMAN |
| Immunogen Region | 680-880 |
| Immunogen Sequence | QNVTAEDTDSIGLALFAPHS SRNYQQHWILVTCQALGEQV IALSVGNKPSLTNPFPAVEP AVVKFVCAPPSRLTLAPVYT SPQLDMSCPLLQQNKQVVPV SSHRNPRLDLAAYDQEGRRF DNFSSLSIQWESTRPVLASI EPELPMQLVSQDDESGQKKL HGLQAILVHEASGTTAITAT ATGYQESHLSSARTKQPHDP L |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 680-880 of human NUP210 (NP_079199.2). |
Additional Info
| Tissue Specificity | Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. |
| Post Translational Modifications | N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides. Phosphorylated at Ser-1881 in mitosis specifically.not phosphorylated in interphase. |
| Function | Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. |
| Protein Name | Nuclear Pore Membrane Glycoprotein 210Nuclear Pore Protein Gp210Nuclear Envelope Pore Membrane Protein Pom 210Pom210Nucleoporin Nup210Pore Membrane Protein Of 210 Kda |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-159227Reactome: R-HSA-159230Reactome: R-HSA-159231Reactome: R-HSA-159236Reactome: R-HSA-165054Reactome: R-HSA-168271Reactome: R-HSA-168276Reactome: R-HSA-168325Reactome: R-HSA-168333Reactome: R-HSA-170822Reactome: R-HSA-180746Reactome: R-HSA-180910Reactome: R-HSA-191859Reactome: R-HSA-3108214Reactome: R-HSA-3232142Reactome: R-HSA-3301854Reactome: R-HSA-3371453Reactome: R-HSA-4085377Reactome: R-HSA-4551638Reactome: R-HSA-4570464Reactome: R-HSA-4615885Reactome: R-HSA-5578749Reactome: R-HSA-5619107Reactome: R-HSA-6784531Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9705671 |
| Cellular Localisation | NucleusNuclear Pore ComplexNucleus MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Nuclear Pore Membrane Glycoprotein 210 antibodyAnti-Nuclear Pore Protein Gp210 antibodyAnti-Nuclear Envelope Pore Membrane Protein Pom 210 antibodyAnti-Pom210 antibodyAnti-Nucleoporin Nup210 antibodyAnti-Pore Membrane Protein Of 210 Kda antibodyAnti-NUP210 antibodyAnti-KIAA0906 antibodyAnti-PSEC0245 antibody |
Information sourced from Uniprot.org