Anti-NUCB1 antibody (302-461 aa) (STJ11106829)

SKU:
STJ11106829

£112.50 - £524.50
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:2000-1:5000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: NUCB1
Gene ID: 4924
Uniprot ID: NUCB1_HUMAN
Immunogen Region: 302-461 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 302-461 of human NUCB1 (NP_006175.2).
Immunogen Sequence: KNVDTNQDRLVTLEEFLAST QRKEFGDTGEGWETVEMHPA YTEEELRRFEEELAAREAEL NAKAQRLSQETEALGRSQGR LEAQKRELQQAVLHMEQRKQ QQQQQQGHKAPAAHPEGQLK FHPDTDDVPVPAPAGDQKEV DTSEKKLLERLPEVEVPQHL
Tissue Specificity Expressed both in fetal and adult heart, lung, liver, kidney and brain, and in adult skeletal muscle, placenta and pancreas.
Post Translational Modifications O-glycosylated.
Function Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins).
Protein Name Nucleobindin-1
Calnuc
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Golgi Apparatus
Cis-Golgi Network Membrane
Peripheral Membrane Protein
Lumenal Side
Cytoplasm
Secreted
A Small Fraction Of The Protein May Be Cytoplasmic
Alternative Antibody Names Anti-Nucleobindin-1 antibody
Anti-Calnuc antibody
Anti-NUCB1 antibody
Anti-NUC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance