| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-NTE (Internal) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments gave an approx 75kDa band in lysates of cell lines HeLa and Kelly after 2µg/ml antibody staining. Please note that currently we cannot find an explanation in th |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PNPLA6 |
| Gene ID: | 10908 |
| Uniprot ID: | PLPL6_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_006693.3 |
| Immunogen Sequence: | YQGRQTSSIFEAAKQ |
| Post Translational Modifications | Glycosylated. |
| Function | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Catalyzes the hydrolysis of several naturally occurring membrane-associated lipids. Hydrolyzes lysophospholipids and monoacylglycerols, preferring the 1-acyl to the 2-acyl isomer. Does not catalyze hydrolysis of di- or triacylglycerols or fatty acid amides. |
| Protein Name | Patatin-Like Phospholipase Domain-Containing Protein 6Neuropathy Target Esterase |
| Database Links | Reactome: R-HSA-6814848 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative Antibody Names | Anti-Patatin-Like Phospholipase Domain-Containing Protein 6 antibodyAnti-Neuropathy Target Esterase antibodyAnti-PNPLA6 antibodyAnti-NTE antibody |
Information sourced from Uniprot.org
