| Post Translational Modifications | Phosphorylation at Ser-569 interferes with homohexamerization. |
| Function | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling. |
| Protein Name | Vesicle-Fusing AtpaseN-Ethylmaleimide-Sensitive Fusion ProteinNem-Sensitive Fusion ProteinVesicular-Fusion Protein Nsf |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-416993Reactome: R-HSA-6807878Reactome: R-HSA-6811434Reactome: R-HSA-6811438Reactome: R-HSA-6811440 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Vesicle-Fusing Atpase antibodyAnti-N-Ethylmaleimide-Sensitive Fusion Protein antibodyAnti-Nem-Sensitive Fusion Protein antibodyAnti-Vesicular-Fusion Protein Nsf antibodyAnti-NSF antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and ATF2 knockout (KO) 293T cells, using [KO Validated] ATF2 Rabbit polyclonal antibody (STJ22702) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/99177/383848/STJ22702_1__38112.1713152438.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and ATF2 knockout (KO) 293T cells, using [KO Validated] ATF2 Rabbit polyclonal antibody (STJ22702) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
