| Host: |
Mouse |
| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
| Short Description : |
Mouse monoclonal antibody anti-Palmitoleoyl-Protein Carboxylesterase Notum is suitable for use in ELISA research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
SAA1845 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2a |
| Formulation: |
0.01M PBS |
| Purification: |
Protein A/G purified from cell culture supernatant |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
| Function | Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors. |
| Protein Name | Palmitoleoyl-Protein Carboxylesterase NotumHnotum |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-5362798Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Palmitoleoyl-Protein Carboxylesterase Notum antibodyAnti-Hnotum antibodyAnti-NOTUM antibodyAnti-OK antibodyAnti-SW-CL.30 antibody |
Information sourced from Uniprot.org
