| Host: | Mouse |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
| Short Description : | Mouse monoclonal anti-Palmitoleoyl-Protein Carboxylesterase Notum for use in ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | SAA1845 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | 0.01M PBS, pH 7.4. |
| Purification: | Protein A/G purified from cell culture supernatant |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
| Gene Symbol: | NOTUM |
| Gene ID: | 147111 |
| Uniprot ID: | NOTUM_HUMAN |
| Function | Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors. |
| Protein Name | Palmitoleoyl-Protein Carboxylesterase NotumHnotum |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-5362798Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Palmitoleoyl-Protein Carboxylesterase Notum antibodyAnti-Hnotum antibodyAnti-NOTUM antibodyAnti-OK antibodyAnti-SW-CL.30 antibody |
Information sourced from Uniprot.org
