Anti-NOTUM antibody [SAA1845] (STJA0020273)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Palmitoleoyl-Protein Carboxylesterase Notum antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1845 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | NOTUM |
| Gene ID | 147111 |
| Uniprot ID | NOTUM_HUMAN |
Additional Info
| Function | Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors. |
| Protein Name | Palmitoleoyl-Protein Carboxylesterase NotumHnotum |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-5362798Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Palmitoleoyl-Protein Carboxylesterase Notum antibodyAnti-Hnotum antibodyAnti-NOTUM antibodyAnti-OK antibodyAnti-SW-CL.30 antibody |
Information sourced from Uniprot.org