| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Nucleolar protein 8 (1118-1167) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NOL8 |
| Gene ID: | 55035 |
| Uniprot ID: | NOL8_HUMAN |
| Immunogen Region: | 1118-1167 |
| Specificity: | Nop132 Polyclonal Antibody detects endogenous levels of Nop132 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NOL8. AA range:1118-1167 |
| Tissue Specificity | Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle. |
| Post Translational Modifications | Phosphorylated. |
| Function | Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells. |
| Protein Name | Nucleolar Protein 8Nucleolar Protein Nop132 |
| Cellular Localisation | NucleusNucleolusLocalizes In The Nucleolar-Organizing Region During Ribosome Biogenesis |
| Alternative Antibody Names | Anti-Nucleolar Protein 8 antibodyAnti-Nucleolar Protein Nop132 antibodyAnti-NOL8 antibodyAnti-C9orf34 antibodyAnti-NOP132 antibody |
Information sourced from Uniprot.org