| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-NMNAT3 (149-162) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.1-0.3µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
NMNAT3 |
| Gene ID: |
349565 |
| Uniprot ID: |
NMNA3_HUMAN |
| Immunogen Region: |
149-162 |
| Accession Number: |
NP_835471.1; NP_001186976.1 |
| Specificity: |
This antibody is expected to recognize both reported isoforms (NP_835471.1; NP_001186976.1). |
| Immunogen Sequence: |
QHNIHLAKEPVQNE |
| Function | Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form.nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury. |
| Protein Name | Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase 3Nmn/Namn Adenylyltransferase 3Nicotinamide-Nucleotide Adenylyltransferase 3Nmn Adenylyltransferase 3Nicotinate-Nucleotide Adenylyltransferase 3Namn Adenylyltransferase 3Pyridine Nucleotide Adenylyltransferase 3Pnat-3 |
| Database Links | Reactome: R-HSA-196807 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase 3 antibodyAnti-Nmn/Namn Adenylyltransferase 3 antibodyAnti-Nicotinamide-Nucleotide Adenylyltransferase 3 antibodyAnti-Nmn Adenylyltransferase 3 antibodyAnti-Nicotinate-Nucleotide Adenylyltransferase 3 antibodyAnti-Namn Adenylyltransferase 3 antibodyAnti-Pyridine Nucleotide Adenylyltransferase 3 antibodyAnti-Pnat-3 antibodyAnti-NMNAT3 antibodyAnti-FKSG76 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
