| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NEUROG3 |
| Gene ID: | 50674 |
| Uniprot ID: | NGN3_HUMAN |
| Immunogen Region: | 1-214 |
| Immunogen Sequence: | MTPQPSGAPTVQVTRETERS FPRASEDEVTCPTSAPPSPT RTRGNCAEAEEGGCRGAPRK LRARRGGRSRPKSELALSKQ RRSRRKKANDRERNRMHNLN |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human NEUROG3 (NP_066279.2). |
| Function | Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. |
| Protein Name | Neurogenin-3Ngn-3Class A Basic Helix-Loop-Helix Protein 7Bhlha7Protein Atonal Homolog 5 |
| Database Links | Reactome: R-HSA-210744Reactome: R-HSA-210746 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Neurogenin-3 antibodyAnti-Ngn-3 antibodyAnti-Class A Basic Helix-Loop-Helix Protein 7 antibodyAnti-Bhlha7 antibodyAnti-Protein Atonal Homolog 5 antibodyAnti-NEUROG3 antibodyAnti-ATOH5 antibodyAnti-BHLHA7 antibodyAnti-NGN3 antibody |
Information sourced from Uniprot.org
