Anti-NEUROG3 antibody (1-214) (STJ24747)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NEUROG3 (1-214) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NEUROG3 |
| Gene ID | 50674 |
| Uniprot ID | NGN3_HUMAN |
| Immunogen Region | 1-214 |
| Immunogen Sequence | MTPQPSGAPTVQVTRETERS FPRASEDEVTCPTSAPPSPT RTRGNCAEAEEGGCRGAPRK LRARRGGRSRPKSELALSKQ RRSRRKKANDRERNRMHNLN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human NEUROG3 (NP_066279.2). |
Additional Info
| Function | Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. |
| Protein Name | Neurogenin-3Ngn-3Class A Basic Helix-Loop-Helix Protein 7Bhlha7Protein Atonal Homolog 5 |
| Database Links | Reactome: R-HSA-210744Reactome: R-HSA-210746 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Neurogenin-3 antibodyAnti-Ngn-3 antibodyAnti-Class A Basic Helix-Loop-Helix Protein 7 antibodyAnti-Bhlha7 antibodyAnti-Protein Atonal Homolog 5 antibodyAnti-NEUROG3 antibodyAnti-ATOH5 antibodyAnti-BHLHA7 antibodyAnti-NGN3 antibody |
Information sourced from Uniprot.org