Anti-NECTIN4 antibody [R4P1] (STJA0019601)

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STJA0019601
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Host: Human
Applications: ELISA/WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Human monoclonal antibody anti-Nectin-4 is suitable for use in ELISA and Western Blot research applications.
Clonality : Monoclonal
Clone ID : R4P1
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: Nectin4
Gene ID: 71740
Uniprot ID: NECT4_MOUSE
Function Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Plays a role in the senescence-associated cell size enlargement via SFK/PI3K/Rac1 and thus promotes senescent cell survival. Participates also in the innate immune response by acting as a ligand for the receptor TIGIT to inhibit NK-cell activity.
Protein Name Nectin-4
Ig Superfamily Receptor Lnir
Nectin Cell Adhesion Molecule 4
Poliovirus Receptor-Related Protein 4
Database Links Reactome: R-MMU-418990
Reactome: -MMU-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Adherens Junction
Colocalizes With Afdn At Cadherin-Based Adherens Junctions
Alternative Antibody Names Anti-Nectin-4 antibody
Anti-Ig Superfamily Receptor Lnir antibody
Anti-Nectin Cell Adhesion Molecule 4 antibody
Anti-Poliovirus Receptor-Related Protein 4 antibody
Anti-Nectin4 antibody
Anti-Lnir antibody
Anti-Prr4 antibody
Anti-Pvrl4 antibody

Information sourced from Uniprot.org