Anti-NECTIN4 antibody [R4P1] (STJA0019601)
SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationUnconjugated
IsotypeIgG1
General Information
| Short Description | Human monoclonal Nectin-4 antibody for use in ELISA and WB in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Human |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R4P1 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | Nectin4 |
| Gene ID | 71740 |
| Uniprot ID | NECT4_MOUSE |
Additional Info
| Function | Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Plays a role in the senescence-associated cell size enlargement via SFK/PI3K/Rac1 and thus promotes senescent cell survival. Also participates in the innate immune response by acting as a ligand for the receptor TIGIT to inhibit NK-cell activity. |
| Protein Name | Nectin-4Ig Superfamily Receptor LnirNectin Cell Adhesion Molecule 4Poliovirus Receptor-Related Protein 4 |
| Database Links | Reactome: R-MMU-418990Reactome: -MMU-420597 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionAdherens JunctionColocalizes With Afdn At Cadherin-Based Adherens Junctions |
| Alternative Antibody Names | Anti-Nectin-4 antibodyAnti-Ig Superfamily Receptor Lnir antibodyAnti-Nectin Cell Adhesion Molecule 4 antibodyAnti-Poliovirus Receptor-Related Protein 4 antibodyAnti-Nectin4 antibodyAnti-Lnir antibodyAnti-Prr4 antibodyAnti-Pvrl4 antibody |
Information sourced from Uniprot.org