| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NDUFAF4 |
| Gene ID: | 29078 |
| Uniprot ID: | NDUF4_HUMAN |
| Immunogen Region: | 1-170 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human NDUFAF4 (NP_054884.1). |
| Immunogen Sequence: | MGALVIRGIRNFNLENRAER EISKMKPSVAPRHPSTNSLL REQISLYPEVKGEIARKDEK LLSFLKDVYVDSKDPVSSLQ VKAAETCQEPKEFRLPKDHH FDMINIKSIPKGKISIVEAL TLLNNHKLFPETWTAEKIMQ EYQLEQKDVNSLLKYFVTFE VEIFPPEDKK |
| Post Translational Modifications | Phosphorylated on serine. Prolactin stimulate serine phosphorylation. |
| Function | Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Assembly Factor 4Hormone-Regulated Proliferation-Associated Protein Of 20 Kda |
| Database Links | Reactome: R-HSA-6799198 |
| Cellular Localisation | MitochondrionMembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Assembly Factor 4 antibodyAnti-Hormone-Regulated Proliferation-Associated Protein Of 20 Kda antibodyAnti-NDUFAF4 antibodyAnti-C6orf66 antibodyAnti-HRPAP20 antibodyAnti-HSPC125 antibodyAnti-My013 antibody |
Information sourced from Uniprot.org