• Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-NDRG2 antibody (10-90) (STJ94369)

SKU:
STJ94369

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein NDRG2 (10-90) is suitable for use in Immunohistochemistry, Immunofluorescence, Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NDRG2
Gene ID: 57447
Uniprot ID: NDRG2_HUMAN
Immunogen Region: 10-90
Specificity: NDRG2 Polyclonal Antibody detects endogenous levels of NDRG2 protein.
Immunogen: Synthesized peptide derived from NDRG2. at AA range: 10-90
Tissue Specificity Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues.absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
Function Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.
Protein Name Protein Ndrg2
N-Myc Downstream-Regulated Gene 2 Protein
Protein Syld709613
Cellular Localisation Cytoplasm
Perinuclear Region
Cell Projection
Growth Cone
In Neurons
Seems To Concentrate At Axonal Growth Cone
Perinuclear In Neurons
Alternative Antibody Names Anti-Protein Ndrg2 antibody
Anti-N-Myc Downstream-Regulated Gene 2 Protein antibody
Anti-Protein Syld709613 antibody
Anti-NDRG2 antibody
Anti-KIAA1248 antibody
Anti-SYLD antibody

Information sourced from Uniprot.org

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