Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-NCS1 (91-190) is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S5MR |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NCS1 |
Gene ID: |
23413 |
Uniprot ID: |
NCS1_HUMAN |
Immunogen Region: |
91-190 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 91-190 of human NCS1 (P62166). |
Immunogen Sequence: |
VTSRGTLDEKLRWAFKLYDL DNDGYITRNEMLDIVDAIYQ MVGNTVELPEEENTPEKRVD RIFAMMDKNADGKLTLQEFQ EGSKADPSIVQALSLYDGLV |
Function | Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin. Stimulates PI4KB kinase activity. Involved in long-term synaptic plasticity through its interaction with PICK1. May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel. |
Protein Name | Neuronal Calcium Sensor 1Ncs-1Frequenin HomologFrequenin-Like ProteinFrequenin-Like Ubiquitous Protein |
Cellular Localisation | Golgi ApparatusPostsynaptic DensityCytoplasmPerinuclear RegionCell MembranePeripheral Membrane ProteinMembraneLipid-AnchorAssociated With Golgi StacksPost-Synaptic Densities Of DendritesAnd In The Pre-Synaptic Nerve Terminal At Neuromuscular Junctions |
Alternative Antibody Names | Anti-Neuronal Calcium Sensor 1 antibodyAnti-Ncs-1 antibodyAnti-Frequenin Homolog antibodyAnti-Frequenin-Like Protein antibodyAnti-Frequenin-Like Ubiquitous Protein antibodyAnti-NCS1 antibodyAnti-FLUP antibodyAnti-FREQ antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance