• Western blot analysis of HL-60, using NCR1 antibody (STJ11105718) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-NCR1 antibody (22-254) (STJ11105718)

SKU:
STJ11105718

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Natural Cytotoxicity Triggering Receptor 1 (22-254) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NCR1
Gene ID: 9437
Uniprot ID: NCTR1_HUMAN
Immunogen Region: 22-254
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-254 of human NCR1 (NP_004820.2).
Immunogen Sequence: QQQTLPKPFIWAEPHFMVPK EKQVTICCQGNYGAVEYQLH FEGSLFAVDRPKPPERINKV QFYIPDMNSRMAGQYSCIYR VGELWSEPSNLLDLVVTEMY DTPTLSVHPGPEVISGEKVT FYCRLDTATSMFLLLKEGRS SHVQRGYGKVQAEFPLGPVT TAHRGTYRCFGSYNNHAWSF PSEPVKLLVTGDIENTSLAP EDPTFPADTWGTYLLTTETG LQKDHALWDHTAQ
Tissue Specificity Selectively expressed by both resting and activated NK cells.
Post Translational Modifications N-glycosylated. O-glycosylated.
Function Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Protein Name Natural Cytotoxicity Triggering Receptor 1
Lymphocyte Antigen 94 Homolog
Nk Cell-Activating Receptor
Natural Killer Cell P46-Related Protein
Nk-P46
Nkp46
Hnkp46
Cd Antigen Cd335
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Natural Cytotoxicity Triggering Receptor 1 antibody
Anti-Lymphocyte Antigen 94 Homolog antibody
Anti-Nk Cell-Activating Receptor antibody
Anti-Natural Killer Cell P46-Related Protein antibody
Anti-Nk-P46 antibody
Anti-Nkp46 antibody
Anti-Hnkp46 antibody
Anti-Cd Antigen Cd335 antibody
Anti-NCR1 antibody
Anti-LY94 antibody

Information sourced from Uniprot.org

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