| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NCAM1 |
| Gene ID: | 4684 |
| Uniprot ID: | NCAM1_HUMAN |
| Immunogen Region: | 759-858 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 759-858 of human NCAM1/CD56 (NP_851996.2). |
| Immunogen Sequence: | LCGKAGPGAKGKDMEEGKAA FSKDESKEPIVEVRTEEERT PNHDGGKHTEPNETTPLTEP EKGPVEAKPECQETETKPAP AEVKTVPNDATQTKENESKA |
| Post Translational Modifications | Polysialylated at Asn-459 and Asn-488 by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans. |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. (Microbial infection) Acts as a receptor for Zika virus. |
| Protein Name | Neural Cell Adhesion Molecule 1N-Cam-1Ncam-1Cd Antigen Cd56 |
| Database Links | Reactome: R-HSA-3000178Reactome: R-HSA-375165Reactome: R-HSA-419037Reactome: R-HSA-445144Reactome: R-HSA-5673001Reactome: R-HSA-877300 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 3: Cell MembraneLipid-AnchorGpi-AnchorIsoform 4: Cell MembraneIsoform 5: SecretedIsoform 6: Secreted |
| Alternative Antibody Names | Anti-Neural Cell Adhesion Molecule 1 antibodyAnti-N-Cam-1 antibodyAnti-Ncam-1 antibodyAnti-Cd Antigen Cd56 antibodyAnti-NCAM1 antibodyAnti-NCAM antibody |
Information sourced from Uniprot.org
![Anti-NCAM1 antibody [SM5149] (STJA0005149)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/180200/403641/STJA0005149_1__19957.1738950646.png?c=1 "Anti-NCAM1 antibody [SM5149] (STJA0005149)")
