| Short Description : | Mouse monoclonal anti-Nucleus accumbens-associated protein 1 for use in WB, IHC, IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 6H2 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000IHC 1:200-1:1000ELISA 1:10000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NACC1 |
| Gene ID: | 112939 |
| Uniprot ID: | NACC1_HUMAN |
| Immunogen: | Purified recombinant fragment of human NAC-1 expressed in E. Coli. |
| Specificity: | NAC-1 Monoclonal Antibody detects endogenous levels of NAC-1 protein. |
| Function | Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. |
| Protein Name | Nucleus Accumbens-Associated Protein 1Nac-1Btb/Poz Domain-Containing Protein 14b |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmDistribution In The Cytoplasm Is Dependent On Phosphorylation |
| Alternative Antibody Names | Anti-Nucleus Accumbens-Associated Protein 1 antibodyAnti-Nac-1 antibodyAnti-Btb/Poz Domain-Containing Protein 14b antibodyAnti-NACC1 antibodyAnti-BTBD14B antibodyAnti-NAC1 antibody |
Information sourced from Uniprot.org
