• Immunohistochemistry analysis of paraffin-embedded mammary cancer tissues (left) and ovarian cancer tissues (right) with DAB staining using NAC-1 monoclonal antibody.
  • Western blot analysis using NAC-1 monoclonal antibody against HEK293 (1) and NACC1-hIgGFc transfected HEK293 (2) cell lysate.

Anti-NACC1 antibody [6H2] (STJ98265)

SKU:
STJ98265

£139.00 - £336.00
Current Stock:
Host: Mouse
Applications: WB/IHC/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Nucleus accumbens-associated protein 1 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 6H2
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NACC1
Gene ID: 112939
Uniprot ID: NACC1_HUMAN
Specificity: NAC-1 Monoclonal Antibody detects endogenous levels of NAC-1 protein.
Immunogen: Purified recombinant fragment of human NAC-1 expressed in E. Coli.
Function Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.
Protein Name Nucleus Accumbens-Associated Protein 1
Nac-1
Btb/Poz Domain-Containing Protein 14b
Cellular Localisation Nucleus
Cytoplasm
Distribution In The Cytoplasm Is Dependent On Phosphorylation
Alternative Antibody Names Anti-Nucleus Accumbens-Associated Protein 1 antibody
Anti-Nac-1 antibody
Anti-Btb/Poz Domain-Containing Protein 14b antibody
Anti-NACC1 antibody
Anti-BTBD14B antibody
Anti-NAC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance