| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MYRIP (551-770) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYRIP |
| Gene ID: |
25924 |
| Uniprot ID: |
MYRIP_HUMAN |
| Immunogen Region: |
551-770 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 551-770 of human MYRIP (NP_001271354.1). |
| Immunogen Sequence: |
VSLCNISTEVLKVINATEEL IAGSTGPWESPQVPPDRQKG MFPRGTDQVRLDEQLTSLEE NVYLAAGTVYGLETQLTELE DAARCIHSGTDETHLADLED QVATAAAQVHHAELQISDIE SRISALTIAGLNIAPCVRFT RRRDQKQRTQVQTIDTSRQQ RRKLPAPPVKAEKIETSSVT TIKTFNHNFILQGSSTNRTK ERKGTTKDLMEPALESAVMY |
| Tissue Specificity | Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis. |
| Function | Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release. |
| Protein Name | Rab Effector MyripExophilin-8Myosin-Viia- And Rab-Interacting ProteinSynaptotagmin-Like Protein Lacking C2 Domains CSlac2-CSlp Homolog Lacking C2 Domains C |
| Database Links | Reactome: R-HSA-264876 |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoplasmic VesicleSecretory VesicleIn Presynaptic And Postsynaptic Areas In Photoreceptor Cells And In The Basal Microvilli Of Retinal Pigment Epithelium CellsAssociated With MelanosomesColocalizes With Actin Filaments |
| Alternative Antibody Names | Anti-Rab Effector Myrip antibodyAnti-Exophilin-8 antibodyAnti-Myosin-Viia- And Rab-Interacting Protein antibodyAnti-Synaptotagmin-Like Protein Lacking C2 Domains C antibodyAnti-Slac2-C antibodyAnti-Slp Homolog Lacking C2 Domains C antibodyAnti-MYRIP antibodyAnti-SLAC2C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
