| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYOT |
| Gene ID: | 9499 |
| Uniprot ID: | MYOTI_HUMAN |
| Immunogen Region: | 259-314 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 259-314 of human MYOT (NP_001129412.1). |
| Immunogen Sequence: | RPNQTLPAPKQLRVRPTFSK YLALNGKGLNVKQAFNPEGE FQRLAAQSGLYESEEL |
| Tissue Specificity | Expressed in skeletal muscle (at protein level). Expressed in skeletal muscle, heart, bone marrow and thyroid gland. |
| Function | Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells. |
| Protein Name | Myotilin57 Kda Cytoskeletal ProteinMyofibrillar Titin-Like Ig Domains ProteinTitin Immunoglobulin Domain Protein |
| Cellular Localisation | Cell MembraneSarcolemmaCytoplasmCytoskeletonMyofibrilSarcomereZ LineSarcomericAlso Localized To The SarcolemmaColocalizes With Myoz1 At The Z-Lines In Skeletal Muscle |
| Alternative Antibody Names | Anti-Myotilin antibodyAnti-57 Kda Cytoskeletal Protein antibodyAnti-Myofibrillar Titin-Like Ig Domains Protein antibodyAnti-Titin Immunoglobulin Domain Protein antibodyAnti-MYOT antibodyAnti-TTID antibody |
Information sourced from Uniprot.org