| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYO5A |
| Gene ID: | 4644 |
| Uniprot ID: | MYO5A_HUMAN |
| Immunogen Region: | 950-1150 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human MYO5A (NP_000250.3). |
| Immunogen Sequence: | LTNLEGIYNSETEKLRSDLE RLQLSEEEAKVATGRVLSLQ EEIAKLRKDLEQTRSEKKCI EEHADRYKQETEQLVSNLKE ENTLLKQEKEALNHRIVQQA KEMTETMEKKLVEETKQLEL DLNDERLRYQNLLNEFSRLE ERYDDLKEEMTLMVHVPKPG HKRTDSTHSSNESEYIFSSE IAEMEDIPSRTEEPSEKKVP L |
| Tissue Specificity | Detected in melanocytes. |
| Function | Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Can hydrolyze ATP in the presence of actin, which is essential for its function as a motor protein. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation. |
| Protein Name | Unconventional Myosin-VaDilute Myosin Heavy Chain - Non-MuscleMyosin Heavy Chain 12Myosin-12Myoxin |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-2029482Reactome: R-HSA-264876Reactome: R-HSA-9664422Reactome: R-HSA-9824585 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Unconventional Myosin-Va antibodyAnti-Dilute Myosin Heavy Chain - Non-Muscle antibodyAnti-Myosin Heavy Chain 12 antibodyAnti-Myosin-12 antibodyAnti-Myoxin antibodyAnti-MYO5A antibodyAnti-MYH12 antibody |
Information sourced from Uniprot.org
