Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-MYO5A (950-1150) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MYO5A |
Gene ID: | 4644 |
Uniprot ID: | MYO5A_HUMAN |
Immunogen Region: | 950-1150 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human MYO5A (NP_000250.3). |
Immunogen Sequence: | LTNLEGIYNSETEKLRSDLE RLQLSEEEAKVATGRVLSLQ EEIAKLRKDLEQTRSEKKCI EEHADRYKQETEQLVSNLKE ENTLLKQEKEALNHRIVQQA KEMTETMEKKLVEETKQLEL DLNDERLRYQNLLNEFSRLE ERYDDLKEEMTLMVHVPKPG HKRTDSTHSSNESEYIFSSE IAEMEDIPSRTEEPSEKKVP L |
Tissue Specificity | Detected in melanocytes. |
Function | Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation. |
Protein Name | Unconventional Myosin-Va Dilute Myosin Heavy Chain - Non-Muscle Myosin Heavy Chain 12 Myosin-12 Myoxin |
Database Links | Reactome: R-HSA-1445148 Reactome: R-HSA-2029482 Reactome: R-HSA-264876 Reactome: R-HSA-9664422 |
Alternative Antibody Names | Anti-Unconventional Myosin-Va antibody Anti-Dilute Myosin Heavy Chain - Non-Muscle antibody Anti-Myosin Heavy Chain 12 antibody Anti-Myosin-12 antibody Anti-Myoxin antibody Anti-MYO5A antibody Anti-MYH12 antibody |
Information sourced from Uniprot.org