| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S8MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:500-1:5000IF/ICC:1:400-1:1600ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYH11 |
| Gene ID: | 4629 |
| Uniprot ID: | MYH11_HUMAN |
| Immunogen Region: | 1160-1313 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1313 of human SMMHC/MYH11 (NP_002465.1). |
| Immunogen Sequence: | DSTATQQELRAKREQEVTVL KKALDEETRSHEAQVQEMRQ KHAQAVEELTEQLEQFKRAK ANLDKNKQTLEKENADLAGE LRVLGQAKQEVEHKKKKLEA QVQELQSKCSDGERARAELN DKVHKLQNEVESVTGMLNEA EGKAIKLAKDVASL |
| Tissue Specificity | Smooth muscle.expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles. |
| Function | Muscle contraction. |
| Protein Name | Myosin-11Myosin Heavy Chain 11Myosin Heavy Chain - Smooth Muscle IsoformSmmhc |
| Database Links | Reactome: R-HSA-3928663Reactome: R-HSA-416572Reactome: R-HSA-445355Reactome: R-HSA-5625740Reactome: R-HSA-5625900Reactome: R-HSA-5627117Reactome: R-HSA-5627123 |
| Cellular Localisation | MelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage IvThick Filaments Of The Myofibrils |
| Alternative Antibody Names | Anti-Myosin-11 antibodyAnti-Myosin Heavy Chain 11 antibodyAnti-Myosin Heavy Chain - Smooth Muscle Isoform antibodyAnti-Smmhc antibodyAnti-MYH11 antibodyAnti-KIAA0866 antibody |
Information sourced from Uniprot.org