Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MYH11 (1680-1979) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:100-1:500IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MYH11 |
Gene ID: |
4629 |
Uniprot ID: |
MYH11_HUMAN |
Immunogen Region: |
1680-1979 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1680-1979 of human SMMHC/SMMHC/MYH11 (NP_001035203.1). |
Immunogen Sequence: |
ATAKENEKKAKSLEADLMQL QEDLAAAERARKQADLEKEE LAEELASSLSGRNALQDEKR RLEARIAQLEEELEEEQGNM EAMSDRVRKATQQAEQLSNE LATERSTAQKNESARQQLER QNKELRSKLHEMEGAVKSKF KSTIAALEAKIAQLEEQVEQ EAREKQAATKSLKQKDKKLK EILLQVEDERKMAEQYKEQA EKGNARVKQLKRQLEEAEEE SQRINANRRKLQRELDEAT |
Tissue Specificity | Smooth muscle.expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles. |
Function | Muscle contraction. |
Protein Name | Myosin-11Myosin Heavy Chain 11Myosin Heavy Chain - Smooth Muscle IsoformSmmhc |
Database Links | Reactome: R-HSA-3928663Reactome: R-HSA-416572Reactome: R-HSA-445355Reactome: R-HSA-5625740Reactome: R-HSA-5625900Reactome: R-HSA-5627117Reactome: R-HSA-5627123 |
Cellular Localisation | MelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage IvThick Filaments Of The Myofibrils |
Alternative Antibody Names | Anti-Myosin-11 antibodyAnti-Myosin Heavy Chain 11 antibodyAnti-Myosin Heavy Chain - Smooth Muscle Isoform antibodyAnti-Smmhc antibodyAnti-MYH11 antibodyAnti-KIAA0866 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance