| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Myeloid-derived growth factor is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYDGF |
| Gene ID: |
56005 |
| Uniprot ID: |
MYDGF_HUMAN |
| Specificity: |
This antibody detects endogenous levels of MYDGF at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human MYDGF |
| Function | Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis. |
| Protein Name | Myeloid-Derived Growth FactorMydgf |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | SecretedEndoplasmic Reticulum-Golgi Intermediate CompartmentEndoplasmic ReticulumGolgi ApparatusThe C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Myeloid-Derived Growth Factor antibodyAnti-Mydgf antibodyAnti-MYDGF antibodyAnti-C19orf10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
