| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Myb-binding protein 1A is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYBBP1A |
| Gene ID: |
10514 |
| Uniprot ID: |
MBB1A_HUMAN |
| Specificity: |
This antibody detects endogenous levels of MYBBP1A at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human MYBBP1A |
| Function | May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter. Has a role in rRNA biogenesis together with PWP1. |
| Protein Name | Myb-Binding Protein 1a |
| Database Links | Reactome: R-HSA-5250924 |
| Cellular Localisation | CytoplasmNucleusNucleolusShuttles Between The Nucleus And CytoplasmNuclear Import May Be Mediated By Kpna2While Export Appears To Depend Partially On Xpo1/Crm1Predominantly Nucleolar |
| Alternative Antibody Names | Anti-Myb-Binding Protein 1a antibodyAnti-MYBBP1A antibodyAnti-P160 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
