| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MXI1 |
| Gene ID: | 4601 |
| Uniprot ID: | MXI1_HUMAN |
| Immunogen Region: | 76-295 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 76-295 of human MXI1 (NP_569157.2). |
| Immunogen Sequence: | LLEAASYLEQIEKENKKCEH GYASSFPSMPSPRLQHSKPP RRLSRAQKHSSGSSNTSTAN RSTHNELEKNRRAHLRLCLE RLKVLIPLGPDCTRHTTLGL LNKAKAHIKKLEEAERKSQH QLENLEREQRFLKWRLEQLQ GPQEMERIRMDSIGSTISSD RSDSEREEIEVDVESTEFSH GEVDNISTTSISDIDDHSSL PSIGSDEGYSSASVKLSFTS |
| Tissue Specificity | High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. |
| Function | Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACGATG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX. |
| Protein Name | Max-Interacting Protein 1Max Interactor 1Class C Basic Helix-Loop-Helix Protein 11Bhlhc11 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Max-Interacting Protein 1 antibodyAnti-Max Interactor 1 antibodyAnti-Class C Basic Helix-Loop-Helix Protein 11 antibodyAnti-Bhlhc11 antibodyAnti-MXI1 antibodyAnti-BHLHC11 antibody |
Information sourced from Uniprot.org