| Function | Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression. |
| Protein Name | Interferon-Induced Gtp-Binding Protein Mx2Interferon-Regulated Resistance Gtp-Binding Protein MxbMyxovirus Resistance Protein 2P78-Related Protein |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-909733 |
| Cellular Localisation | CytoplasmNucleusNuclear Pore ComplexLocalization To Nuclear Pores Requires Gtp-Binding |
| Alternative Antibody Names | Anti-Interferon-Induced Gtp-Binding Protein Mx2 antibodyAnti-Interferon-Regulated Resistance Gtp-Binding Protein Mxb antibodyAnti-Myxovirus Resistance Protein 2 antibodyAnti-P78-Related Protein antibodyAnti-MX2 antibody |
Information sourced from Uniprot.org
