Anti-MUTYH antibody (476aa C-Term) (STJ140046)

SKU:
STJ140046
$130.41 - $607.89
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Host: Goat
Applications: WB
Reactivity: Human/Mouse/Rat/Bovine/Canine/Chicken/Avian/Donkey/Feline/Goat/Guinea Pig/Hamster/Horse/Porcine/Rabbit/Sheep/Simian
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal MutY homolog (E. coli) (476aa C-Term) antibody for use in WB in human, mouse, rat, bovine, canine, chicken, avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep and simian samples. Datasheet included with di
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 20% Glycerol and 0.05% Sodium Azide.
Purification: This antibody is epitope-affinity purified from goat antiserum.
Concentration: 3 mg/mL
Dilution Range: WB 1:500-1:2000
Ferreira JV Rosa Soares A Ramalho JS et al. PLoS One. 2019 Oct. PMID: 31613922
Storage Instruction: For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
Gene Symbol: MUTYH
Gene ID: 4595
Uniprot ID: MUTYH_HUMAN
Immunogen Region: 476aa C-Term
Accession Number: ENSG00000132781
Specificity: In 293HEK cells transfected with cds plasmid (myc-his-Mutyh) detects a band of 50 kDa by Western blot.
Immunogen: Purified recombinant peptide derived from within residues 476 aa to the C-terminus of human Mutyh produced in E. coli.
Immunogen Sequence: MKKVFRVYQGQQPGTCMGSK KKVFRVYQGQQPGTCMGSKR KVFRVYQGQQPGTCMGSKRS
Function Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.
Protein Name Adenine Dna Glycosylase
Muty Homolog
Hmyh
Database Links Reactome: R-HSA-110330
Reactome: R-HSA-110331
Reactome: R-HSA-110357
Reactome: R-HSA-9608287 Q9UIF7-3
Reactome: R-HSA-9608290
Cellular Localisation Nucleus
Mitochondrion
Alternative Antibody Names Anti-Adenine Dna Glycosylase antibody
Anti-Muty Homolog antibody
Anti-Hmyh antibody
Anti-MUTYH antibody
Anti-MYH antibody

Information sourced from Uniprot.org