| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Musashi 1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | ZN127 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Purification: | Affinity Chromatography |
| Concentration: | 0.5-1.0 mg/mL |
| Dilution Range: | IHC 1:50-1:100 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | MSI1 |
| Gene ID: | 4440 |
| Uniprot ID: | MSI1H_HUMAN |
| Immunogen: | Full length human recombinant protein of human MSI1 (NP_002433) produced in HEk293T cell. |
| Tissue Specificity | Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. |
| Function | RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-GAU(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. |
| Protein Name | Rna-Binding Protein Musashi Homolog 1Musashi-1 |
| Database Links | Reactome: R-HSA-9010553 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Rna-Binding Protein Musashi Homolog 1 antibodyAnti-Musashi-1 antibodyAnti-MSI1 antibody |
Information sourced from Uniprot.org
