Anti-Musashi 1 antibody [ZN127] (STJA0033369)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenFull length human recombinant protein of human MSI1 (NP_002433) produced in HEk293T cell.
General Information
| Short Description | Mouse monoclonal anti-Musashi 1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZN127 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 0.5-1.0 mg/mL |
| Purification | Affinity Chromatography |
| Dilution Range | IHC 1:50-1:100 |
| Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MSI1 |
| Gene ID | 4440 |
| Uniprot ID | MSI1H_HUMAN |
| Immunogen | Full length human recombinant protein of human MSI1 (NP_002433) produced in HEk293T cell. |
Additional Info
| Tissue Specificity | Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. |
| Function | RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-GAU(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. |
| Protein Name | Rna-Binding Protein Musashi Homolog 1Musashi-1 |
| Database Links | Reactome: R-HSA-9010553 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Rna-Binding Protein Musashi Homolog 1 antibodyAnti-Musashi-1 antibodyAnti-MSI1 antibody |
Information sourced from Uniprot.org