![Anti-MUM1 antibody [MRQ-8] (STJ16100401)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149118/346739/STJ16100401_1__79751.1681998831.jpg?c=1 "Anti-MUM1 antibody [MRQ-8] (STJ16100401)")
![Anti-MUM1 antibody [MRQ-8] (STJ16100401)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149118/346739/STJ16100401_1__79751.1681998831.jpg?c=1 "Anti-MUM1 antibody [MRQ-8] (STJ16100401)")
Anti-MUM1 antibody [MRQ-8] (STJ16100401)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
General Information
| Short Description | Mouse monoclonal anti-MUM1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | MRQ-8 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Dilution Range | IHC 1:100 – 1:500 |
| Formulation | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | IRF4 |
| Gene ID | 3662 |
| Uniprot ID | IRF4_HUMAN |
Additional Info
| Tissue Specificity | Lymphoid cells. |
| Post Translational Modifications | Phosphorylation by ROCK2 regulates IL-17 and IL-21 production. |
| Function | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes. |
| Protein Name | Interferon Regulatory Factor 4Irf-4Lymphocyte-Specific Interferon Regulatory FactorLsirfMultiple Myeloma Oncogene 1Nf-Em5 |
| Database Links | Reactome: R-HSA-6785807Reactome: R-HSA-877300Reactome: R-HSA-909733Reactome: R-HSA-9725371Reactome: R-HSA-9824585 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Interferon Regulatory Factor 4 antibodyAnti-Irf-4 antibodyAnti-Lymphocyte-Specific Interferon Regulatory Factor antibodyAnti-Lsirf antibodyAnti-Multiple Myeloma Oncogene 1 antibodyAnti-Nf-Em5 antibodyAnti-IRF4 antibodyAnti-MUM1 antibody |
Information sourced from Uniprot.org