• Anti-MUM1 antibody [MRQ-43] (STJ16100460)

Anti-MUM1 antibody [MRQ-43] (STJ16100460)

SKU:
STJ16100460

£1,327.50
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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-MUM1 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: MRQ-43
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Dilution Range: IHC 1:100 – 1:500
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: IRF4
Gene ID: 3662
Uniprot ID: IRF4_HUMAN
Tissue Specificity Lymphoid cells.
Post Translational Modifications Phosphorylation by ROCK2 regulates IL-17 and IL-21 production.
Function Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
Protein Name Interferon Regulatory Factor 4
Irf-4
Lymphocyte-Specific Interferon Regulatory Factor
Lsirf
Multiple Myeloma Oncogene 1
Nf-Em5
Database Links Reactome: R-HSA-6785807
Reactome: R-HSA-877300
Reactome: R-HSA-909733
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Interferon Regulatory Factor 4 antibody
Anti-Irf-4 antibody
Anti-Lymphocyte-Specific Interferon Regulatory Factor antibody
Anti-Lsirf antibody
Anti-Multiple Myeloma Oncogene 1 antibody
Anti-Nf-Em5 antibody
Anti-IRF4 antibody
Anti-MUM1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance