• STJ71483 Immunofluorescence analysis of paraformaldehyde fixed HepG2 cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml) , showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
  • STJ71483 Immunofluorescence analysis of paraformaldehyde fixed Caco-2 cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml) , showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).

Anti-MUC13 antibody (Internal) (STJ71483)

SKU:
STJ71483-100

£303.50
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Host: Goat
Applications: Pep-ELISA/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-MUC13 (Internal) is suitable for use in ELISA and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IF-Strong expression of the protein seen in the cytoplasm of HepG2 and Caco-2 cells. 10µg/ml
ELISA-antibody detection limit dilution 1:4000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: MUC13
Gene ID: 56667
Uniprot ID: MUC13_HUMAN
Immunogen Region: Internal
Accession Number: NP_149038.3
Immunogen Sequence: DCKSDLQRPNPQ
Post Translational Modifications Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homooligomerization into dimers is dependent on intrachain disulfide bonds. Highly N-glycosylated.
Function Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
Protein Name Mucin-13
Muc-13
Down-Regulated In Colon Cancer 1
Database Links Reactome: R-HSA-5083625
Reactome: R-HSA-5083632
Reactome: R-HSA-5083636
Reactome: R-HSA-5621480
Reactome: R-HSA-913709
Reactome: R-HSA-9696264
Reactome: R-HSA-9696270
Reactome: R-HSA-9696273
Reactome: R-HSA-977068
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Apical Cell Membrane
Secreted
Also Exists As A Soluble Form
Alternative Antibody Names Anti-Mucin-13 antibody
Anti-Muc-13 antibody
Anti-Down-Regulated In Colon Cancer 1 antibody
Anti-MUC13 antibody
Anti-DRCC1 antibody
Anti-RECC antibody
Anti-UNQ6194 antibody
Anti-PRO20221 antibody

Information sourced from Uniprot.org

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