| Host: | Goat |
| Applications: | Pep-ELISA/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MUC13 (Internal) is suitable for use in ELISA and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.IF: Strong expression of the protein seen in the cytoplasm of HepG2 and Caco-2 cells. Recommended concentration: 10µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MUC13 |
| Gene ID: | 56667 |
| Uniprot ID: | MUC13_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_149038.3 |
| Immunogen Sequence: | DCKSDLQRPNPQ |
| Post Translational Modifications | Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homooligomerization into dimers is dependent on intrachain disulfide bonds. Highly N-glycosylated. |
| Function | Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. |
| Protein Name | Mucin-13Muc-13Down-Regulated In Colon Cancer 1 |
| Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-913709Reactome: R-HSA-9696264Reactome: R-HSA-9696270Reactome: R-HSA-9696273Reactome: R-HSA-977068 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinApical Cell MembraneSecretedAlso Exists As A Soluble Form |
| Alternative Antibody Names | Anti-Mucin-13 antibodyAnti-Muc-13 antibodyAnti-Down-Regulated In Colon Cancer 1 antibodyAnti-MUC13 antibodyAnti-DRCC1 antibodyAnti-RECC antibodyAnti-UNQ6194 antibodyAnti-PRO20221 antibody |
Information sourced from Uniprot.org