Anti-MTRFR antibody (STJA0008435)

SKU:
STJA0008435

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Mitochondrial translation release factor in rescue is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MTRFR
Gene ID: 91574
Uniprot ID: MTRFR_HUMAN
Specificity: This antibody detects endogenous levels of C12orf65 at Human, Mouse
Immunogen: Synthesized peptide derived from human C12orf65
Post Translational Modifications Methylation of glutamine in the GGQ triplet by HEMK1.
Function Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation. As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue.
Protein Name Mitochondrial Translation Release Factor In Rescue
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Mitochondrial Translation Release Factor In Rescue antibody
Anti-MTRFR antibody
Anti-C12orf65 antibody
Anti-My030 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance