Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MTNR1A (281-350) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:1000-1:5000IHC-P 1:100-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MTNR1A |
Gene ID: |
4543 |
Uniprot ID: |
MTR1A_HUMAN |
Immunogen Region: |
281-350 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 281-350 of human MTNR1A (NP_005949.1). |
Immunogen Sequence: |
YYMAYFNSCLNAIIYGLLNQ NFRKEYRRIIVSLCTARVFF VDSSNDVADRVKWKPSPLMT NNNVVKVDSV |
Tissue Specificity | Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus. |
Function | High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Protein Name | Melatonin Receptor Type 1aMel-1a-RMel1a Receptor |
Database Links | Reactome: R-HSA-373076Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Melatonin Receptor Type 1a antibodyAnti-Mel-1a-R antibodyAnti-Mel1a Receptor antibodyAnti-MTNR1A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance