| Short Description : | Rabbit polyclonal anti-Methylenetetrahydrofolate reductase (314-363) for use in WB, ELISA and IHC in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTHFR |
| Gene ID: | 4524 |
| Uniprot ID: | MTHR_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MTHFR. AA range:314-363 |
| Immunogen Region: | 314-363 |
| Specificity: | MTHFR Polyclonal Antibody detects endogenous levels of MTHFR protein. |
| Post Translational Modifications | Phosphorylation of an N-terminal serine-rich phosphorylation region increases sensitivity to S-adenosylmethionine and inhibition. |
| Function | Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Represents a key regulatory connection between the folate and methionine cycles (Probable). |
| Protein Name | Methylenetetrahydrofolate ReductaseNadph |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Methylenetetrahydrofolate Reductase antibodyAnti-Nadph antibodyAnti-MTHFR antibody |
Information sourced from Uniprot.org
