• Western blot analysis of lysates from Jurkat cells, using MTERF Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HUVECcells using MTERF antibody.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MTERF Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-MTERF1 antibody (267-316) (STJ94273)

SKU:
STJ94273

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Transcription termination factor 1, mitochondrial (267-316) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MTERF1
Gene ID: 7978
Uniprot ID: MTEF1_HUMAN
Immunogen Region: 267-316
Specificity: mTERF Polyclonal Antibody detects endogenous levels of mTERF protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human MTERF. AA range:267-316
Post Translational Modifications Phosphoprotein with mostly four phosphate groups. While the DNA-binding activity is unaffected by the phosphorylation state, only the phosphorylated form of the protein is active for termination activity. Functioning seems to be regulated by phosphorylation.
Function Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene.this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.
Protein Name Transcription Termination Factor 1 - Mitochondrial
Mitochondrial Transcription Termination Factor 1
Mterf
Mterf1
Database Links Reactome: R-HSA-163316
Reactome: R-HSA-2151201
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Transcription Termination Factor 1 - Mitochondrial antibody
Anti-Mitochondrial Transcription Termination Factor 1 antibody
Anti-Mterf antibody
Anti-Mterf1 antibody
Anti-MTERF1 antibody
Anti-MTERF antibody

Information sourced from Uniprot.org

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