• Immunofluorescence analysis of U-2 OS cells using [KO Validated] MTCH2 Rabbit polyclonal antibody (STJ114800) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of NIH-3T3 cells using [KO Validated] MTCH2 Rabbit polyclonal antibody (STJ114800) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of lysates from wild type (WT) and MTCH2 knockout (KO) HeLa (KO) cells, using [KO Validated] MTCH2 Rabbit polyclonal antibody (STJ114800) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.

Anti-MTCH2 antibody (30-175) (STJ114800)

SKU:
STJ114800

£129.50 - £639.50
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Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MTCH2 (30-175) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MTCH2
Gene ID: 23788
Uniprot ID: MTCH2_HUMAN
Immunogen Region: 30-175
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-175 of human MTCH2 (NP_055157.1).
Immunogen Sequence: VGYEPLPPTIGRNIFGRQVC QLPGLFSYAQHIASIDGRRG LFTGLTPRLCSGVLGTVVHG KVLQHYQESDKGEELGPGNV QKEVSSSFDHVIKETTREMI ARSAATLITHPFHVITLRSM VQFIGRESKYCGLCDSIITI YREEGI
Function Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane. Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins. Also acts as a receptor for the truncated form of pro-apoptotic BH3-interacting domain death agonist (p15 BID) and has therefore a critical function in apoptosis. Regulates the quiescence/cycling of hematopoietic stem cells (HSCs). Acts as a regulator of mitochondrial fusion, essential for the naive-to-primed interconversion of embryonic stem cells (ESCs). Acts as a regulator of lipid homeostasis and has a regulatory role in adipocyte differentiation and biology.
Protein Name Mitochondrial Carrier Homolog 2
Met-Induced Mitochondrial Protein
Cellular Localisation Mitochondrion Outer Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Mitochondrial Carrier Homolog 2 antibody
Anti-Met-Induced Mitochondrial Protein antibody
Anti-MTCH2 antibody
Anti-MIMP antibody
Anti-HSPC032 antibody

Information sourced from Uniprot.org

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